Regenerative Cell Therapies

Highly powerful and minimally invasive
Alleviate pain caused by OA and sports injuries
Natural healing of damaged tissues
Longer lasting effects vs. PRP therapy
Avoid surgery

The OrthoBiologics Clinic is one of the only clinics in the UK to provide the revolutionary new ACP^SVF Cell Therapy, a highly advanced adipose derived stem cell therapy. It is also a more advanced and refined treatment than other systems available.

How does it work?

The use of Regenerative Cell Therapies harness the power of the organic building blocks of the human body, known as stem cells, which are capable of transforming into a variety of tissue cells, including cartilage, bone and tendon. At The OrthoBiologics Clinic, our highly skilled doctors extract adult (mesenchymal) stem cells derived from our patient’s bone marrow or fat tissue to provide an infusion of fresh, new regenerative cells that are injected into the affected area to help promote healing and the formation of new tissues. Regenerative Cell Therapy, therefore, helps preserve the joint itself, alleviating related symptoms and avoiding the need for surgery.

Book a consultation with us today to enable one of our regenerative medicine doctors to examine your tendon injury, joint pain or back aches to determine which of our tailored Orthobiologic treatment plans would provide the best option for you.

ACP^SVF Cell Therapy

The OrthoBiologics Clinic is one of the first clinics in the UK to offer this revolutionary new type of regenerative cell therapy for arthritic joint pain and tendinopathies, which combines the advantages of an increased concentration of healing growth factors in PRP and regenerative cells that are derived from body fat (adipose tissue).

Adipose tissue contains thousands of times more regenerative cells than bone marrow, which also release numerous signal substances that could play an important role in accelerating tissue regeneration. Specifically, the part of adipose tissue that contains the regenerative cells is called the Stromal Vascular Fraction (SVF), which can be obtained using a highly specialised, minimally-invasive procedure by our trained doctors at The OrthoBiologics Clinic.

Once extracted and then combined with PRP from the patient, this powerful biological substance is injected into the affected area under ultrasound guidance. The entire procedure is carried out all on the same day, completed within around 60 minutes, with the patient under sedation.

Research has already demonstrated how well PRP and SVF work together making it one of the most potent treatments currently available. All of our patients are invited to enrol into an outcome study when they decide to undergo treatment. This reporting tool enables us to record your progress following treatment, as well as enable the clinical team to monitor you through your recovery and contribute to furthering science in the field of regenerative medicine.

FAQs

Where does the Stromal Vascular Fraction come from?

What does the ACP^SVF Cell Therapy procedure involve?

This typically involves being admitted as a day case with the procedure being carried out in a sterile environment. Adipose tissue is harvested usually from the abdomen or flanks. The procedure is carried out using a needle and syringe under local anaesthesia with sedation. Once the required volume of 30 ml of adipose tissue is obtained, this is then concentrated through a specialised centrifuge and added to platelet rich plasma producing the bioactive solution for injection. This can then be injected into the affected area under ultrasound guidance for accuracy.

Who might benefit from ACP^SVF Cell Therapy procedures?

Is ACP^SVF Cell Therapy safe?

What are the side effects of ACP^SVF Cell Therapy?

Typically, this includes discomfort at the site of adipose aspiration and at the site where the concentrate is injected. Some patients experience some discomfort during injection, but this is well tolerated under sedation. Some patients report swelling at the site of injection, but this usually settles at 48 hours. Occasionally there may be bruising at the site of adipose harvesting, but this usually resolves after a few days.

Are the ACP^SVF Cell Therapy injections painful?

As this procedure is usually carried out under sedation, with the addition of intravenous pain killer, very few patients experience any pain. Local anaesthetic solution is injected before any adipose harvesting is done which helps reduce any pain during the procedure and into the recovery period. Afterwards you will be given post procedure instructions which will include a list of analgesics (pain killers) you can use after treatment.

Bone Marrow Cell Therapy (BMAC)

A typical procedure normally takes around 60 minutes and involves the harvesting of bone marrow stem cells directly from the patient, called bone marrow aspiration, usually from the iliac crest (pelvic bone) or femur (thigh bone). The procedure is carried out using a needle and syringe under local anaesthesia and sedation in a sterile environment at the clinic. The system we use at The OrthoBiologics Clinic is a closed system meaning that the bone marrow does not come into contact with anything between extraction and reinjection bringing the risk of infection to an absolute minimum. Once the required volume of bone marrow is obtained, it is then concentrated through a specialised centrifuge situated in the treatment room whilst the patient is still present. This produces an injectable solution, called Bone Marrow Aspirate Concentrate (BMAC), which is rich in regenerative cells and growth factors. It is then carefully injected into the patient to the affected areas requiring treatment under ultrasound guidance for accuracy.

FAQs

Where do the stem cells come from?

The stem cells found inside the bone marrow are aspirated through a needle and concentrated through a special centrifuge that provides a solution for injection.

What does the BMAC procedure involve?

It involves the harvesting of bone marrow directly from the patient. usually from a long bone or the iliac crest (pelvic bone). The procedure is carried out using a needle and syringe under local anaesthesia and sedation in a sterile environment. Once the required volume of bone marrow is obtained, this is then concentrated through a specialised centrifuge, producing the solution for injection. This concentrate is then injected into the affected area under ultrasound guidance for accuracy.

Who might benefit from these BMAC procedures?

Is BMAC safe?

What are the side effects of BMAC?

Typically, this includes tenderness at the site of bone marrow aspiration and at the site where the concentrate is injected. Some patients experience some discomfort during injection, but this is well tolerated under sedation. Some patients report swelling at the site of injection, but this usually settles at 48 hours. Occasionally there may be bruising at the site of bone marrow harvesting, but this resolves after a few days.

Are the BMAC injections painful?

As this procedure is usually carried out under sedation, with the addition of intravenous pain killer, very few patients experience any pain. Local anaesthetic is also used for bone marrow harvesting, which helps reduce any pain during the recovery period. Afterwards, you will be given post-procedure instructions which will include a list of analgesics (pain killers) you can use after treatment.

Regenerative Cell Therapies

How does it work?

ACPSVF Cell Therapy

Bone Marrow Cell Therapy (BMAC)

FAQs

ACP^SVF Cell Therapy